Sensitivity and specificity of 14 SARS-CoV-2 serological assays and their diagnostic potential in RT-PCR negative COVID-19 infections

Comparing the Diagnostic Power of Chest CT Scan and RT-PCR in Diagnosis of COVID-19

Background and purpose: Proper diagnosis of patients with COVID-19 is one of the challenges in medical centers. RT-PCR is the standard and reference test in diagnosis of patients with COVID-19. This study aimed at accelerating the correct diagnosis of COVID-19 and the diagnostic power of chest CT scan and RT-PCR. Materials and methods: This study was performed in 569 patients with COVID-19 adm...

CHALLENGES OF LABORATORY SAMPLING AND DIAGNOSIS OF SARS-COV-2 VIRUS OF DISEASE (COVID-19)

Background & Aims: Given the prevalence of SARS-CoV-2 worldwide, it is essential to identify people infected with the virus and determine its different types to control the global outbreak of COVID-19. The results of the studies are controversial, so this study examines these diagnostic challenges, including the types of diagnostic methods, the type and time of sampling, and even the clinical c...

Covid-19 Serological Tests: A Journey from Denial of Reality to Conclusive Insights

In response to the outbreak of COVID-19, caused by the SARS-CoV-2 virus, several tests are needed for diagnosis of acute illness, contact tracking, diagnosis of asymptomatic infections, and assessment of herd immunity. While PCR is the standard test in acute type, serological tests have been developed and used to meet diagnostic needs due to the widespread prevalence of the disease. Unlike the...

SARS-CoV-2 and COVID-19, evidence from a literature review: review article

  SARS-CoV-2 emerging from Wuhan, China is a member of the Coronaviridae family, which has so far infected and killed many people. The SARS-CoV-2 pandemic affected various aspects of life in Iran and Worldwide, and governments have imposed quarantines and travel bans on an unprecedented scale. The virus causes COVID-19, which can spread through close contact with the infected person, contaminat...

Specificity and performance of diagnostic PCR assays.